Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden
Marco Duering, Marek J. Konieczny, Steffen Tiedt, Ebru Baykara, Anil Man Tuladhar, Esther van Leijsen, Philippe Lyrer, Stefan T. Engelter, Benno Gesierich, Melanie Achmüller, Christian Barro, Ruth Adam, Michael Ewers, Martin Dichgans, Jens Kuhle, Frank-Erik de Leeuw, Nils Peters
J Stroke. 2018;20(2):228-238. Published online 2018 May 31 DOI: https://doi.org/10.5853/jos.2017.02565
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Yumi Yamamoto, Yi-Chu Liao, Yi-Chung Lee, Masafumi Ihara, Jay Chol Choi
Journal of Clinical Neurology.2023; 19(1): 12. CrossRef Neurofilament light level correlates with brain atrophy, and cognitive and motor performance
Marge Kartau, Susanna Melkas, Joonas Kartau, Anne Arola, Hanna Laakso, Johanna Pitkänen, Juha Lempiäinen, Juha Koikkalainen, Jyrki Lötjönen, Antti Korvenoja, Matti Ahlström, Sanna-Kaisa Herukka, Timo Erkinjuntti, Hanna Jokinen
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International Journal of Molecular Sciences.2023; 24(2): 1233. CrossRef Serum neurofilament light chain levels are associated with early neurological deterioration in minor ischemic stroke
Jie Li, Ping Zhang, Yalan Zhu, Yong Duan, Shan Liu, Jie Fan, Hong Chen, Chun Wang, Xingyang Yi
Frontiers in Neurology.2023;[Epub] CrossRef Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel disease
Joyce R. Chong, Saima Hilal, Nicholas J. Ashton, Thomas K. Karikari, Anthonin Reilhac, Henri Vrooman, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Christopher P. Chen, Mitchell K. P. Lai
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Priyadarshi Prajjwal, Mohammed Dheyaa Marsool Marsool, Pugazhendi Inban, Bhavya Sharma, Shahnaz Asharaf, Soumya Aleti, Srikanth Gadam, Ahmed Sermed Al Sakini, Dalia Dhia Hadi
Disease-a-Month.2023; 69(5): 101557. CrossRef Plasma neurofilament light and brain volumetric outcomes among middle-aged urban adults
May A. Beydoun, Nicole Noren Hooten, Hind A. Beydoun, Jordan Weiss, Ana I. Maldonado, Leslie I. Katzel, Christos Davatzikos, Rao P. Gullapalli, Stephen L. Seliger, Guray Erus, Michele K. Evans, Alan B. Zonderman, Shari R. Waldstein
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Oluchi Ekenze, Adlin Pinheiro, Serkalem Demissie, Hugo J. Aparicio, Andreas Charidimou, Alexa S. Beiser, Claudia L. Satizabal, Tiffany Kautz, Charles DeCarli, Steven Greenberg, Sudha Seshadri, Jose R. Romero
Journal of Alzheimer's Disease.2023; 95(3): 1133. CrossRef Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective
Stefano Salvioli, Maria Sofia Basile, Leonardo Bencivenga, Sara Carrino, Maria Conte, Sarah Damanti, Rebecca De Lorenzo, Eleonora Fiorenzato, Alessandro Gialluisi, Assunta Ingannato, Angelo Antonini, Nicola Baldini, Miriam Capri, Simone Cenci, Licia Iacov
Ageing Research Reviews.2023; 91: 102044. CrossRef Molecular biomarkers for vascular cognitive impairment and dementia
Satoshi Hosoki, Gurpreet K. Hansra, Tharusha Jayasena, Anne Poljak, Karen A. Mather, Vibeke S. Catts, Ruslan Rust, Abhay Sagare, Jason C. Kovacic, Amy Brodtmann, Anders Wallin, Berislav V. Zlokovic, Masafumi Ihara, Perminder S. Sachdev
Nature Reviews Neurology.2023; 19(12): 737. CrossRef Axonal Injury Partially Mediates Associations Between Increased Left Ventricular Mass Index and White Matter Damage
Elizabeth E. Moore, Omair A. Khan, Niranjana Shashikumar, Kimberly R. Pechman, Dandan Liu, Susan P. Bell, Sangeeta Nair, James G. Terry, Katherine A. Gifford, Adam W. Anderson, Bennett A. Landman, Kaj Blennow, Henrik Zetterberg, Timothy J. Hohman, John Je
Stroke.2022; 53(3): 808. CrossRef Neurofilament Light Chain as a Biomarker in Cerebral Small-Vessel Disease
Nils Peters
Molecular Diagnosis & Therapy.2022; 26(1): 1. CrossRef Vasculocentric Axonal NfH in Small Vessel Disease
Adam Anad, Miriam K Barker, Jessica A Katanga, Konstantinos Arfanakis, Leslie R Bridges, Margaret M Esiri, Jeremy D Isaacs, Sonja Prpar Mihevc, Anthony C Pereira, Julie A Schneider, Atticus H Hainsworth
Journal of Neuropathology & Experimental Neurology.2022; 81(3): 182. CrossRef Cerebrospinal fluid neurofilament light chain is a marker of aging and white matter damage
Karin L. Meeker, Omar H. Butt, Brian A. Gordon, Anne M. Fagan, Suzanne E. Schindler, John C. Morris, Tammie L.S. Benzinger, Beau M. Ances
Neurobiology of Disease.2022; 166: 105662. CrossRef Early plasma biomarker dynamic profiles are associated with acute ischemic stroke outcomes
Manuel Correia, Isabel Silva, Denis Gabriel, Joel Simrén, Angelo Carneiro, Sara Ribeiro, Hugo Mota Dória, Ricardo Varela, Ana Aires, Karolina Minta, Rui Antunes, Rui Felgueiras, Pedro Castro, Kaj Blenow, Rui Magalhães, Henrik Zetterberg, Luis F. Maia
European Journal of Neurology.2022; 29(6): 1630. CrossRef Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults
Alison E. Fohner, Traci M. Bartz, Russell P. Tracy, Hieab H.H. Adams, Joshua C. Bis, Luc Djousse, Claudia L. Satizabal, Oscar L. Lopez, Sudha Seshadri, Kenneth J. Mukamal, Lewis H. Kuller, Bruce M. Psaty, W.T. Longstreth
Neurology.2022;[Epub] CrossRef Neurodegeneration and convergent factors contributing to the deterioration of the cytoskeleton in Alzheimer's disease, cerebral ischemia and multiple sclerosis (Review)
Johanna Gutiérrez‑Vargas, John Castro‑Álvarez, Jose Zapata‑Berruecos, Komal Abdul‑Rahim, Anibal Arteaga‑Noriega
Biomedical Reports.2022;[Epub] CrossRef Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation
Alexandros A. Polymeris, Fabrice Helfenstein, Pascal Benkert, Stefanie Aeschbacher, David Leppert, Michael Coslovsky, Eline Willemse, Sabine Schaedelin, Manuel R. Blum, Nicolas Rodondi, Tobias Reichlin, Giorgio Moschovitis, Jens Wuerfel, Gian Marco De Mar
Frontiers in Neuroscience.2022;[Epub] CrossRef Plasma β-Amyloid, Total-Tau, and Neurofilament Light Chain Levels and the Risk of Stroke
Alis Heshmatollah, Lana Fani, Peter J. Koudstaal, Mohsen Ghanbari, M. Arfan Ikram, M. Kamran Ikram
Neurology.2022;[Epub] CrossRef The Association of Serum Neurofilament Light Chain and Acute Ischaemic Stroke Is Influenced by Effective Revascularization
Fa-Ying Zhou, Dong-Wan Chen, Hui-Yun Li, Chi Zhu, Ying-Ying Shen, Ze-Yan Peng, Ling Li, Xian-Le Bu, Gui-Hua Zeng, Meng Zhang, Yan-Jiang Wang, Wang-Sheng Jin, Yuzhen Xu
Disease Markers.2022; 2022: 1. CrossRef Contrast agent‐free state‐of‐the‐art magnetic resonance imaging on cerebral small vessel disease – Part 2: Diffusion tensor imaging and functional magnetic resonance imaging
Pedro Henrique Rodrigues da Silva, André Monteiro Paschoal, Kaio Felippe Secchinatto, Maria Clara Zanon Zotin, Antônio Carlos dos Santos, Anand Viswanathan, Octavio M. Pontes‐Neto, Renata Ferranti Leoni
NMR in Biomedicine.2022;[Epub] CrossRef Abnormalities of retinal structure and microvasculature are associated with cerebral white matter hyperintensities
Xirui Zhou, Tao Li, Wensheng Qu, Dengji Pan, Qianwen Qiu, Lingshan Wu, Jing Zhao, Zhiyuan Yu, Huang Hao, Xiang Luo
European Journal of Neurology.2022; 29(8): 2289. CrossRef Temporal Patterning of Neurofilament Light as a Blood-Based Biomarker for Stroke: A Systematic Review and Meta-Analysis
Jasmin D. Sanchez, Richard A. Martirosian, Katherine T. Mun, Davis S. Chong, Irene Lorenzo Llorente, Timo Uphaus, Klaus Gröschel, Teresa A. Wölfer, Steffen Tiedt, Jason D. Hinman
Frontiers in Neurology.2022;[Epub] CrossRef Increased Neurofilament Light Chain Is Associated with Increased Risk of Long-Term Mortality in Cerebral Small Vessel Disease
Mina A. Jacob, Nils Peters, Mengfei Cai, Marco Duering, Stefan T. Engelter, Jens Kuhle, Frank-Erik de Leeuw, Anil M. Tuladhar
Journal of Stroke.2022; 24(2): 296. CrossRef Plasma Neurofilament Light Chain Is Associated with Cognitive Impairment after Posterior Circulation Stroke
Lianyan Jiang, Zhiqiang Wang, Rongyu Wang, Mao Li, Yaodan Zhang, Dongdong Yang, Weidong Pan
Evidence-Based Complementary and Alternative Medicine.2022; 2022: 1. CrossRef Serum Neurofilament Light Chain in Patients With Atrial Fibrillation
Karl Sjölin, Julia Aulin, Lars Wallentin, Niclas Eriksson, Claes Held, Kim Kultima, Jonas Oldgren, Joachim Burman
Journal of the American Heart Association.2022;[Epub] CrossRef Brain MRI in Monogenic Cerebral Small Vessel Diseases:
A Practical Handbook
Leonardo Ulivi, Mirco Cosottini, Gianmichele Migaleddu, Giovanni Orlandi, Nicola Giannini, Gabriele Siciliano, Michelangelo Mancuso
Current Molecular Medicine.2022; 22(4): 300. CrossRef Association of plasma biomarkers of amyloid and neurodegeneration with cerebrovascular disease and Alzheimer's disease
Jonathan Graff-Radford, Michelle M. Mielke, Ekaterina I. Hofrenning, Naomi Kouri, Timothy G. Lesnick, Christina M. Moloney, Alejandro Rabinstein, Janisse N. Cabrera-Rodriguez, Darren M. Rothberg, Scott A. Przybelski, Ronald C. Petersen, David S. Knopman,
Neurobiology of Aging.2022; 119: 1. CrossRef Association of Serum GFAP with Functional and Neurocognitive Outcome in Sporadic Small Vessel Disease
André Huss, Ahmed Abdelhak, Benjamin Mayer, Hayrettin Tumani, Hans-Peter Müller, Katharina Althaus, Jan Kassubek, Markus Otto, Albert C. Ludolph, Deniz Yilmazer-Hanke, Hermann Neugebauer
Biomedicines.2022; 10(8): 1869. CrossRef Neurofilaments in neurologic disorders and beyond
Gloria Mak, Suresh Menon, Jian-Qiang Lu
Journal of the Neurological Sciences.2022; 441: 120380. CrossRef Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE)
Hugh S. Markus, Wiesje M. van Der Flier, Eric E. Smith, Philip Bath, Geert Jan Biessels, Emily Briceno, Amy Brodtman, Hugues Chabriat, Christopher Chen, Frank-Erik de Leeuw, Marco Egle, Aravind Ganesh, Marios K. Georgakis, Rebecca F. Gottesman, Sun Kwon,
JAMA Neurology.2022; 79(11): 1187. CrossRef Determination of Blood NOTCH3 Extracellular Domain and Jagged-1 Levels in Healthy Subjects
Hyesung Kim, Bogun Jang, Yang-Ji Kim, Jay Chol Choi
International Journal of Molecular Sciences.2022; 23(18): 10547. CrossRef The age-dependent associations of white matter hyperintensities and neurofilament light in early- and late-stage Alzheimer's disease
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Neurobiology of Aging.2021; 97: 10. CrossRef Cognitive Impairment in Patients with Stroke
Caitlin E. D'Souza, Melanie R. F. Greenway, Jonathan Graff-Radford, James F. Meschia
Seminars in Neurology.2021; 41(01): 075. CrossRef Serum Neurofilament Light Chain Levels in the Intensive Care Unit: Comparison between Severely Ill Patients with and without Coronavirus Disease 2019
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Yong-Sheng Zheng, Chong Sun, Rong Wang, Ne Chen, Su-Shan Luo, Jian-Ying Xi, Jia-Hong Lu, Chong-Bo Zhao, Yu-Xin Li, Lei Zhou, Jie Lin
Scientific Reports.2021;[Epub] CrossRef Combination of Serum Neurofilament Light Chain Levels and MRI Markers to Predict Cognitive Function in Ischemic Stroke
Yuan Peng, Qianfeng Li, Lei Qin, Yating He, Xun Luo, Yue Lan, Xin Chen, Xin Wang, Qing Mei Wang
Neurorehabilitation and Neural Repair.2021; 35(3): 247. CrossRef Association of Plasma Neurofilament Light With Small Vessel Disease Burden in Nondemented Elderly
Yi Qu, Chen-Chen Tan, Xue-Ning Shen, Hong-Qi Li, Mei Cui, Lan Tan, Qiang Dong, Jin-Tai Yu
Stroke.2021; 52(3): 896. CrossRef Neurofilament light chain predicts future dementia risk in cerebral small vessel disease
Marco Egle, Laurence Loubiere, Aleksandra Maceski, Jens Kuhle, Nils Peters, Hugh S Markus
Journal of Neurology, Neurosurgery & Psychiatry.2021; 92(6): 582. CrossRef Neurofilament light chain in a phase 2 clinical trial of ibudilast in progressive multiple sclerosis
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Multiple Sclerosis Journal.2021; 27(13): 2014. CrossRef Cognitive impairment in patients with cerebrovascular disease: A white paper from the links between stroke ESO Dementia Committee
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European Stroke Journal.2021; 6(1): 5. CrossRef Cerebrospinal Fluid and Blood Neurofilament Light Chain Protein in Prion Disease and Other Rapidly Progressive Dementias: Current State of the Art
Samir Abu-Rumeileh, Piero Parchi
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Cerebral Circulation - Cognition and Behavior.2021; 2: 100013. CrossRef Plasma neurofilament light chain levels predict improvement in late phase after stroke
Anna Stokowska, Lina Bunketorp Käll, Christian Blomstrand, Joel Simrén, Michael Nilsson, Henrik Zetterberg, Kaj Blennow, Milos Pekny, Marcela Pekna
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Neurology.2021; 96(20): 944. CrossRef Serum neurofilament light chain levels are associated with stroke severity and functional outcome in patients undergoing endovascular therapy for large vessel occlusion
Jan Rahmig, Katja Akgün, Erik Simon, Matthias Gawlitza, Christian Hartmann, Timo Siepmann, Lars-Peder Pallesen, Jessica Barlinn, Volker Puetz, Tjalf Ziemssen, Kristian Barlinn
Journal of the Neurological Sciences.2021; 429: 118063. CrossRef Neurofilament Light Chain Protein Is a Predictive Biomarker for Stroke After Surgical Repair for Acute Type A Aortic Dissection
Kai Zhang, Zhu Wang, Kai Zhu, Songbo Dong, Xudong Pan, Lizhong Sun, Qing Li
Frontiers in Cardiovascular Medicine.2021;[Epub] CrossRef Factors influencing serum neurofilament light chain levels in normal aging
Marisa Koini, Lukas Pirpamer, Edith Hofer, Arabella Buchmann, Daniela Pinter, Stefan Ropele, Christian Enzinger, Pascal Benkert, David Leppert, Jens Kuhle, Reinhold Schmidt, Michael Khalil
Aging.2021; 13(24): 25729. CrossRef Relationship of Neurofilament Light (NfL) and Cognitive Performance in a Sample of Mexican Americans with Normal Cognition, Mild Cognitive Impairment and Dementia
James R. Hall, Leigh A. Johnson, Melissa Peterson, David Julovich, Tori Como, Sid E. O’Bryant
Current Alzheimer Research.2021; 17(13): 1214. CrossRef Neurofilament Light Chain as a Biomarker, and Correlation with Magnetic Resonance Imaging in Diagnosis of CNS-Related Disorders
Zahra Alirezaei, Mohammad Hossein Pourhanifeh, Sarina Borran, Majid Nejati, Hamed Mirzaei, Michael R. Hamblin
Molecular Neurobiology.2020; 57(1): 469. CrossRef New Treatment Approaches to Modify the Course of Cerebral Small Vessel Diseases
Eric E. Smith, Hugh S. Markus
Stroke.2020; 51(1): 38. CrossRef Neurofilaments: The C-Reactive Protein of Neurology
Kate L. Lambertsen, Catarina B. Soares, David Gaist, Helle H. Nielsen
Brain Sciences.2020; 10(1): 56. CrossRef Combined Transcriptomic and Proteomic Analyses of Cerebral Frontal Lobe Tissue Identified RNA Metabolism Dysregulation as One Potential Pathogenic Mechanism in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CAD
Marie-Françoise Ritz, Paul Jenoe, Leo Bonati, Stefan Engelter, Philippe Lyrer, Nils Peters
Current Neurovascular Research.2020; 16(5): 481. CrossRef Serum neurofilament light levels in normal aging and their association with morphologic brain changes
Michael Khalil, Lukas Pirpamer, Edith Hofer, Margarete M. Voortman, Christian Barro, David Leppert, Pascal Benkert, Stefan Ropele, Christian Enzinger, Franz Fazekas, Reinhold Schmidt, Jens Kuhle
Nature Communications.2020;[Epub] CrossRef Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy
Gargi Banerjee, Gareth Ambler, Ashvini Keshavan, Ross W. Paterson, Martha S. Foiani, Jamie Toombs, Amanda Heslegrave, John C. Dickson, Francesco Fraioli, Ashley M. Groves, Michael P. Lunn, Nick C. Fox, Henrik Zetterberg, Jonathan M. Schott, David J. Werri
Journal of Alzheimer's Disease.2020; 74(4): 1189. CrossRef Plasma neurofilament light chain and glial fibrillary acidic protein predict stroke in CADASIL
Chih-Hao Chen, Yu-Wen Cheng, Ya-Fang Chen, Sung-Chun Tang, Jiann-Shing Jeng
Journal of Neuroinflammation.2020;[Epub] CrossRef Acute Neurofilament Light Chain Plasma Levels Correlate With Stroke Severity and Clinical Outcome in Ischemic Stroke Patients
Helle H. Nielsen, Catarina B. Soares, Sofie S. Høgedal, Jonna S. Madsen, Rikke B. Hansen, Alex A. Christensen, Charlotte Madsen, Bettina H. Clausen, Lars Henrik Frich, Matilda Degn, Christian Sibbersen, Kate L. Lambertsen
Frontiers in Neurology.2020;[Epub] CrossRef Novel decision algorithm to discriminate parkinsonism with combined blood and imaging biomarkers
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Parkinsonism & Related Disorders.2020; 77: 57. CrossRef Serum Neurofilament Light Chain Is Associated with Incident Lacunes in Progressive Cerebral Small Vessel Disease
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Journal of Stroke.2020; 22(3): 369. CrossRef Elevated Levels of Serum Neurofilament Light Chain Associated with Cognitive Impairment in Vascular Dementia
Weibin Ma, Jingjing Zhang, Jialei Xu, Depeng Feng, Xiaoling Wang, Fengyu Zhang, Wen-Jun Tu
Disease Markers.2020; 2020: 1. CrossRef Blood neurofilament light: a critical review of its application to neurologic disease
Christian Barro, Tanuja Chitnis, Howard L. Weiner
Annals of Clinical and Translational Neurology.2020; 7(12): 2508. CrossRef Serum neurofilament light in atrial fibrillation: clinical, neuroimaging and cognitive correlates
Alexandros A Polymeris, Michael Coslovksy, Stefanie Aeschbacher, Tim Sinnecker, Pascal Benkert, Richard Kobza, Jürg Beer, Nicolas Rodondi, Urs Fischer, Giorgio Moschovitis, Andreas U Monsch, Anne Springer, Matthias Schwenkglenks, Jens Wuerfel, Gian Marco
Brain Communications.2020;[Epub] CrossRef Biomarkers Related to Endothelial Dysfunction and Vascular Cognitive Impairment: A Systematic Review
Rui Kleber Martins-Filho, Maria Clara Zotin, Guilherme Rodrigues, Octavio Pontes-Neto
Dementia and Geriatric Cognitive Disorders.2020; 49(4): 365. CrossRef Serum Neurofilament light correlates with CADASIL disease severity and survival
Gido Gravesteijn, Julie W. Rutten, Inge M. W. Verberk, Stefan Böhringer, Michael K. Liem, Jeroen van der Grond, Annemieke Aartsma‐Rus, Charlotte E. Teunissen, Saskia A. J. Lesnik Oberstein
Annals of Clinical and Translational Neurology.2019; 6(1): 46. CrossRef Clinical and research applications of magnetic resonance imaging in the study of CADASIL
Dorothee Schoemaker, Yakeel T. Quiroz, Heirangi Torrico-Teave, Joseph F. Arboleda-Velasquez
Neuroscience Letters.2019; 698: 173. CrossRef CADASIL: new advances in basic science and clinical perspectives
Elisa A. Ferrante, Cornelia D. Cudrici, Manfred Boehm
Current Opinion in Hematology.2019; 26(3): 193. CrossRef Serum Neurofilament Light Chain Concentration Correlates with Infarct Volume but Not Prognosis in Acute Ischemic Stroke
Juha Onatsu, Ritva Vanninen, Pekka Jäkälä, Pirjo Mustonen, Kari Pulkki, Miika Korhonen, Marja Hedman, Henrik Zetterberg, Kaj Blennow, Kina Höglund, Sanna-Kaisa Herukka, Mikko Taina
Journal of Stroke and Cerebrovascular Diseases.2019; 28(8): 2242. CrossRef Asymptomatic Cerebral Small Vessel Disease: Insights from Population-Based Studies
Alvin S. Das, Robert W. Regenhardt, Meike W. Vernooij, Deborah Blacker, Andreas Charidimou, Anand Viswanathan
Journal of Stroke.2019; 21(2): 121. CrossRef Serum NfL (Neurofilament Light Chain) Levels and Incident Stroke in Adults With Diabetes Mellitus
Frederick K. Korley, Jason Goldstick, Mitra Mastali, Jennifer E. Van Eyk, William Barsan, William J. Meurer, Jeremy Sussman, Hayley Falk, Deborah Levine
Stroke.2019; 50(7): 1669. CrossRef Emerging Biomarkers in Vascular Cognitive Impairment and Dementia: From Pathophysiological Pathways to Clinical Application
Virginia Cipollini, Fernanda Troili, Franco Giubilei
International Journal of Molecular Sciences.2019; 20(11): 2812. CrossRef Circulating neurofilament light in ischemic stroke: temporal profile and outcome prediction
Annie Pedersen, Tara M. Stanne, Staffan Nilsson, Sofia Klasson, Lars Rosengren, Lukas Holmegaard, Katarina Jood, Kaj Blennow, Henrik Zetterberg, Christina Jern
Journal of Neurology.2019; 266(11): 2796. CrossRef Plasma Lipid Profiling Identifies Biomarkers of Cerebral Microvascular Disease
Ida Azizkhanian, Sunil A. Sheth, Anthony T. Iavarone, Songmi Lee, Visesha Kakarla, Jason D. Hinman
Frontiers in Neurology.2019;[Epub] CrossRef NfL (Neurofilament Light Chain) Levels as a Predictive Marker for Long-Term Outcome After Ischemic Stroke
Timo Uphaus, Stefan Bittner, Sonja Gröschel, Falk Steffen, Muthuraman Muthuraman, Katrin Wasser, Mark Weber-Krüger, Frauke Zipp, Rolf Wachter, Klaus Gröschel
Stroke.2019; 50(11): 3077. CrossRef Fourth European stroke science workshop
S Debette, D Strbian, JM Wardlaw, HB van der Worp, GJE Rinkel, V Caso, M Dichgans, E Tournier-Lasserve, C Grefkes, PJ Kelly, K Muir, E Berge, DA Trégouët, C Roffe, M Brainin, J Beck, T Steiner, LM de Lau, E Jouvent, R Veltkamp, JC Baron, K Nedeltchev, PM
European Stroke Journal.2018; 3(3): 206. CrossRef
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