ERRATUM: Table Correction: Case Characteristics, Hyperacute Treatment, and Outcome Information from the Clinical Research Center for Stroke-Fifth Division Registry in South Korea

Article information

J Stroke. 2015;17(3):377-378

Publication date (electronic) : 2015 September 30

doi : https://doi.org/10.5853/jos.2015.17.3.377

^aDepartment of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea

^bDepartment of Neurology, Eulji General Hospital, Eulji University, Seoul, Korea

^cDepartment of Neurology, Eulji University Hospital, Daejeon, Korea

^dDepartment of Neurology, Dong-A University Hospital, Busan, Korea

^eDepartment of Neurology, Seoul Medical Center, Seoul, Korea

^fDepartment of Neurology, Soonchunhyang University Hospital Seoul, Seoul, Korea

^gDepartment of Neurology, Yeungnam University Medical Center, Daegu, Korea

^hDepartment of Neurology, Inje University Ilsan Paik Hospital, Goyang, Korea

ⁱDepartment of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea

^jDepartment of Neurology, Dongguk University Ilsan Hospital, Goyang, Korea

^kDepartment of Neurology, Chonnam National University Hospital, Gwangju, Korea

^lDepartment of Neurology, Jeju National University Hospital, Jeju, Korea

^mDepartment of Neurology, Ulsan University Hospital, Ulsan, Korea

ⁿDepartment of Neurology, Chungbuk National University Hospital, Cheongju, Korea

^oDepartment of Neurology, Keimyung University Dongsan Medical Center, Daegu, Korea

^pDepartment of Biostatistics, Korea University, Seoul, Korea

^qClinical Research Center, Asan Medical Center, Seoul, Korea

^rDepartment of Neurology, Seoul National University Hospital, Seoul, Korea

See the Original "Case Characteristics, Hyperacute Treatment, and Outcome Information from the Clinical Research Center for Stroke-Fifth Division Registry in South Korea" in Volume 17 on page 38.

Journal of Stroke 2015;17(1):38-53 http://dx.doi.org/10.5853/jos.2015.17.1.38

On page 47, the definition of stroke progression was erroneously described in the previous version of article, and the correct definition of “stroke progression” is as following;

Corrected Table 5

END event in neurologically stable patients ≥ 24 hours

• May be attributable to peri-lesional edema

• For cases with ≤ 24 hours after onset, END events not attributable to recurrent stroke

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Table 5.

Definitions of outcome variables in the CRCS-5 registry

Outcome variables	Definitions	Operational definitions
END Collected since January 2011	Any new neurological symptoms/signs or neurological worsening within 3 weeks of index stroke	Any of the following;
	Causes of END	1) Increase in total NIHSS score ≥ 2³²
	• Recurrent stroke	2) Increase in NIHSS subscores 1a, 1b, or 1c (level of consciousness) ≥ 1³³
	• Stroke progression	3) Increase in NIHSS subscores 5a, 5b, 6a, or 6b (motor) ≥ 1³²
	• Symptomatic hemorrhagic transformation	4) Any new neurological deficit (even unmeasurable by NIHSS scores)³²
	• Others (deep vein thrombosis, pulmonary embolism, myocardial infarction, etc.)
	• Unknown
Recurrent stroke for END (within 3 weeks of index stroke)^30,32	Development of END associated with new lesions docu- mented by relevant neuroimaging study	• Discrete new lesions documented by diffusion-weighted image or computed tomography
		• If discrete, new lesions within the vascular territory of the index stroke lesion may be counted
		• Do not count for increased volume of the index stroke lesions
		• Donotcountforedema,masseffect,herniation,or hemorrhagic transformation of the index stroke lesions
Recurrent stroke (late recurrence ≥ 3 weeks following index stroke)^29,31,34-36	Rapidly developing clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than of vascular origin³⁷	Data collected through face-to-face or telephone inter- view with the patient or next of kin
		Question: Were you diagnosed with ischemic stroke or hemorrhagic stroke by any doctor after discharge?
Stroke progression³²	END event in neurologically stable patients ≥ 24 hours
	• May be attributable to peri-lesional edema
	• For cases with ≤ 24 hours after onset, END events not attributable to recurrent stroke
Symptomatic hemorrhagic transformation³²	END events attributable to documented hemorrhagic transformation and associated with NIHSS score increase ≥ 4 points
Other causes of END	END events attributable to medical conditions (e.g., deep vein thrombosis, pulmonary embolization, pneumonia, etc.)
Unknown causes of END	END events not specified above
Myocardial infarction		For END events (≤ 3 weeks after index stroke, more than two from below;
		• Typicalchestpain
		• Troponin elevation
		• ECG changes (new ST segment changes, new Q wave, or new left bundle branch block)
		For long-term outcomes (≥ 3 weeks after index stroke), data collected through face-to-face or telephone interview with the patient or next of kin
		• Question: Were you diagnosed with myocardial infarction by any doctors after discharge?
Vascular death	Death due to stroke, myocardial infarction, or sudden death^38,39	Data collected through face-to-face or telephone interview with the patient or next of kin
		• No known non-atherosclerotic cause and definite MI or stroke within 4 weeks before death⁴⁰
		• No known non-atherosclerotic cause and one or both of the following: chest pain within 72 hours of death or a history of chronic ischemic heart disease (in the absence of valvular heart disease or non-ischemic cardiomyopathy)⁴⁰
		• No known non-atherosclerotic cause and death certificate consistent with CHD as underlying cause⁴⁰
Non-vascular death	Death not attributable to stroke, myocardial infarction, or sudden death⁴⁰	Data collected through face-to-face or telephone interview with the patient or next of kin

END, early neurological deterioration; NIHSS, National Institute of Health Stroke Scale; ECG, electrocardiography; MI, myocardial infarction; CHD, coronary heart disease.